MacDrive works with Windows running virtually under macOS Parallels Desktop for Mac or VMware Fusion, with the exception in both cases that the macOS system volume will be inaccessible.
In such cases, the macOS system volume is inaccessible because, as with any operating system, macOS requires exclusive access to any volumes it has mounted.
Please note that you will need to configure your virtualization software to have a particular virtual OS take control of a drive before Windows can use it. This is often in a “Settings” or “Devices” menu. For detailed help with your particular virtualization product and version, please contact the software manufacturer.